SLU-PP-332 5mg

SLU-PP-332 5mg

€34,95
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SLU-PP-332 5mg
  • SLU-PP-332 5mg
  • SLU-PP-332 5mg
SLU-PP-332 5mg

SLU-PP-332 5mg

€34,95

SLU-PP-332 is a novel, synthetic small-molecule drug candidate categorized as an Estrogen-Related Receptor (ERR) agonist, with high selectivity for ERRα, ERRβ, and ERRγ. In preclinical laboratory settings, SLU-PP-332 is investigated for its ability to function as an "exercise mimetic"—activating physiological metabolic pathways typically triggered by endurance exercise without increasing physical activity.

Research Relevance: Investigated for its key role in metabolic reprogramming, oxidative phosphorylation upregulation, and mitochondrial biogenesis, it serves as a prominent compound in metabolic disease and skeletal muscle adaptation studies.

Specifications

Name SLU-PP-332
Type Pan-ERR Agonist (Exercise Mimetic)
Compound Class Synthetic Small Molecule
Purity ≥ 98% (HPLC – COA available)
Molecular Weight 433.45 g/mol
Analyses HPLC, NMR, MS
Format Solid powder / Lyophilized compound
Storage Conditions 2-8°C (short term) or -20°C (long term)

Confidential Lab Data - Specification Sheet

Chemical Formula

C23H19F3N2O3

SLU-PP-332 Key Structural Motifs & Functional Groups
CoreBenzoic
GroupAcid
LinkerAmide
MotifMethyl
AromaticPhenyl
ActiveCF3
IUPAC Chemical Name
4-((2-(4-(trifluoromethyl)phenyl)acetamido)methyl)benzoic acid

SLU-PP-332: Exercise Mimetic in Metabolic Research

SLU-PP-332 has emerged as a groundbreaking focus in metabolic research due to its capacity to directly stimulate orphan nuclear receptors responsible for controlling oxidative muscle genetic programs.

Mechanism: ERR Nuclear Receptor Activation

Estrogen-related receptors (ERRs) act as master transcriptional regulators of cellular energy production and mitochondrial function.

  • Pan-ERR Potency: SLU-PP-332 activates ERRα, ERRβ, and ERRγ, with particular potency toward ERRα, which governs mitochondrial bioenergetics.
  • Mitochondrial Biogenesis: Upregulates the expression of genes involved in electron transport chain complexes, boosting mitochondrial density in skeletal muscle cells.
  • Substrate Switching: Encourages cells to increase fatty acid oxidation (lipid burning) while conserving glycogen stores, mimicking the metabolic response to prolonged endurance training.

Primary Areas of Research

Current laboratory studies focus on several key metabolic and physiological pathways:

1. Metabolic Rate and Body Composition

  • Fat Loss without Muscle Atrophy: Investigated for its ability to decrease fat mass and improve insulin sensitivity while preserving lean muscle mass.
  • Energy Expenditure: Research measures increased resting metabolic rates driven by continuous cellular lipid oxidation.

2. Endurance and Muscle Fiber Transformation

  • Type-I Fiber Conversion: Evaluated for its capacity to shift muscle fibers toward slow-twitch, fatigue-resistant oxidative Type I fibers.
  • Exercise Capacity: Studies report significantly enhanced treadmill endurance and distance metrics in animal models.

3. Cardiovascular & Organ Function

  • Cardiac Energy Homeostasis: Examined for potential therapeutic benefit in models of heart failure and age-related metabolic decline.

For Research Purposes Only

This product is intended strictly for laboratory research.

By purchasing this product, you acknowledge these conditions and agree to follow established research protocols and safety practices.

USE & DISCLAIMER:

For research purposes only.
Not for human use, diagnosis or treatment.
For use only by qualified personnel in a controlled research environment.


By purchasing this product you confirm that you have read and understood these terms and conditions and that you have followed appropriate research practices.

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