Synenergy: 2x CJC-1295 (5mg) + Ipamorelin (10mg)
The GH Secretagogue Stack combines two of the most extensively researched growth hormone-releasing peptides: Ipamorelin and CJC-1295. Operating through two distinct receptor pathways (the GHS-R1a ghrelin receptor and the GHRH receptor, respectively), this combination is widely studied in laboratory settings for its powerful synergistic effect on triggering pulsatile endogenous growth hormone release.
Research Relevance: This stack serves as a foundational research model for cellular growth, protein synthesis, lipid metabolism, and tissue repair via receptor synergy without significant disruption of cortisol or prolactin levels.
Specifications
| Product Name | GH Secretagogue Stack (Ipamorelin + CJC-1295) |
| Bundle Contents | 1x Ipamorelin (10mg) + 2x CJC-1295 (5mg) |
| Type | Synthetic Research Peptides (GHS / GHRH Analog) |
| Purity | ≥ 99% (HPLC – COA available) |
| Molecular Weight | 711.87 g/mol (Ipamorelin) | 3367.90 g/mol (CJC-1295) |
| Analyses | HPLC, MS |
| Format | Lyophilized powder (Vials) |
| Storage Conditions | 2-8°C (short term) or -20°C (long term) |
Confidential Lab Data - Specification Sheet
C38H49N9O5
C152H252N44O42
The Synergy: Dual Receptor Stimulation
In endocrine science, combining Ipamorelin with CJC-1295 is known for its unique synergistic mechanism. Where CJC-1295 functions as a GHRH analog (stimulating natural production), Ipamorelin acts as a selective Ghrelin/GHS-R agonist (triggering the actual pulsatile release). Together, they significantly amplify the pituitary output signal compared to individual peptide application.
Primary Research Areas
1. Growth Hormone & IGF-1 Regulation
- Pulsatile Release: Research focuses on how this combination mimics natural GH pulsatility without exhausting the pituitary axis.
- IGF-1 Amplification: Investigates the elevated circulating IGF-1 levels in the liver that support sustained cellular regeneration.
2. Tissue Repair and Muscle Protein Synthesis
- Muscle & Tendon Recovery: Accelerated protein synthesis in muscle tissues and support for collagen matrix restoration.
- Lipid Metabolism: Stimulation of lipolysis (fat breakdown) mediated through GH-dependent enzymatic pathways.
3. Selectivity & Safety Profile
- Hormonal Neutrality: Unlike older GHRPs, Ipamorelin is noted for its ability to avoid triggering spikes in cortisol, prolactin, or ACTH.