PT-141 10mg
PT-141 (Bremelanotide) 10mg is a synthetic peptide analogue of alpha-MSH (Melanocyte-stimulating hormone). Unlike other substances, PT-141 does not act on the vascular system; instead, research focuses on the activation of melanocortin receptors in the brain to modulate physiological responses.
Specifications
| Name | PT-141 (Bremelanotide) |
| Type | Research Peptide: Melanocortin Agonist |
| Amino Acid Count | 7 |
| Purity | ± 99% (HPLC – COA available) |
| Molecular Weight | 1025.20 g/mol |
| Analysis | HPLC, MS |
| Form | Lyophilized powder |
| Storage Conditions | 2-8°C (short-term) or -20°C (long-term) |
Confidential Lab Data - Specification Sheet
C50H68N14O10
Scientific History
The history of PT-141 (Bremelanotide) is closely tied to research on skin pigmentation. The peptide is a derivative of Melanotan II, a compound originally developed at the University of Arizona to promote skin tanning without exposure to UV radiation.
During clinical trials in the 1990s, researchers observed an unexpected side effect in study participants: a significant increase in libido and sexual arousal. Unlike Melanotan II, Bremelanotide induced these effects without strongly stimulating melanocytes (pigment cells).
Mechanism of Action
PT-141 is distinguished by its neurological mechanism of action. Whereas traditional agents target the cardiovascular system (blood vessels), PT-141 acts directly on the central nervous system by activating melanocortin receptors (specifically MC3R and MC4R) in the hypothalamus. This makes it a fundamental subject of study for research into dopamine-related motivation and sexual response.