Melanotan || / MT-2
€40,00
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Melanotan || / MT-2
€40,00
Melanotan II is a synthetic analogue of the naturally occurring peptide hormone Alpha-Melanocyte-Stimulating Hormone (α-MSH). In scientific research, this cyclic heptapeptide is widely studied for its binding affinity to melanocortin receptors (MC1R through MC5R) and its influence on melanogenesis and systemic physiological responses.
Research Relevance: Investigated for its role in skin pigmentation mechanisms, photoprotection against UV radiation, lipolysis, and central nervous system signaling related to sexual behavior and appetite regulation.
Specifications
| Name | Melanotan II (MT-2) |
| Type | Research Peptide: Cyclic Melanocortin Agonist |
| Amino Acid Count | 7 (Cyclic Heptapeptide) |
| Purity | ± 99% (HPLC – COA available) |
| Molecular Weight | 1024.2 g/mol |
| Analyses | HPLC, MS |
| Format | Lyophilized powder |
| Storage Conditions | 2-8°C (short term) or -20°C (long term) |
Confidential Lab Data - Specification Sheet
Chemical Formula
C50H69N11O9
Melanotan II Amino Acid Sequence (Cyclic Heptapeptide)
1Ac-Nle
2cyclo[Asp
3His
4D-Phe
5Arg
6Trp
7Lys]-NH2
Scientific Background
Developed initially at the University of Arizona, Melanotan II was engineered as a more potent and stable synthetic analog of naturally occurring α-MSH. Its lactam-bridge cyclic structure provides increased resistance to enzymatic degradation compared to linear peptides.
Primary Research Focus Areas
- Melanogenesis & Photoprotection (MC1R): Activates melanocytes to synthesize melanin (primarily eumelanin), serving as a core model for UV radiation protection studies.
- Central Nervous System & Libido (MC3R/MC4R): Crosses the blood-brain barrier to stimulate central melanocortin receptors, investigated for its effects on sexual arousal and erectile signaling.
- Metabolic Modulation: Researched for its role in appetite suppression, energy expenditure, and lipid metabolism via central pathways.